TSV Thermosensitive Gel
|Collagen Composition||Heterologous type I and III collagen gel and
thermogelling synthetic biocompatible copolymer
|Physical form||Low viscosity gel at <8°c and high viscosity gel at >13°c|
|Re-Entry Time||About 4-5 months, depending on grafting site characteristics|
0.5g vial in combination with 0.5cc syringe
Characteristics: The purpose of TSV Gel is to provide mechanical stability to bone substitutes and barrier membranes. TSV Gel is sterilized by Gamma irradiation and is radio-transparent. It contains heterologous type I and III collagen gel with polyunsaturated fatty acids diluted in aqueous solution containing a biocompatible synthetic copolymer that gives TSV Gel thermo-reversible and thermo-gelling properties.
|Handling: TSV Gel must be refrigerated for at least 20 minutes at 4°C before use, in order to reach the low viscosity (LV) phase, which makes it easier to mix with Gen-Os® or Apatos.
At room temperature, the product remains at LV phase for few minutes, whereas once in situ its viscosity quickly increases with body temperature. TSV Gel in LV phase can be used instead of saline for hydrating and mixing with Gen-Os® or Apatos. The result will be a sticky mixture easy to place and extremely stable once in situ.
TSV Gel can also be applied to the rough side of the Evolution membrane to stabilize it during graft covering and whilst suturing.