mp3 Collagenated Bone Mix

Tissue of origin   Heterologous cortico-cancellous collagenated bone mix
Tissue collagen   About 10% (Gel 0)
Physical form   Pre-hydrated granules and collagen gel
Composition   90% granulated mix, 10% collagen gel
Granulometry   600-1000 µm
Re-Entry Time   About 5 months

1 Sterile Syringe, 1cc
3 Sterile Syringes, 0.25cc each
3 Sterile Syringes, 0.5cc each
3 Sterile Syringes, 1cc each

  • Pre-hydrated and ready to use
  • Reduces operatory time and contamination risk
  • Smooth granules prevent damage to sinus membrane
  • Close similarity to human bone
  • Dual composition: mineral collagen
  • Natural porcine origin
  • Gradually resorbable
  • Replaced by abundant new vital bone
  • Ideal for sinus lift and ridge preservation
  • Safe and biocompatible: used in over 30,000 surgeries

Characteristics: heterologous origin biomaterial made of 600-1000 µm pre-hydrated collagenated cortico-cancellous granules, properly mixed with OsteoBiol Gel 0. Thus, it is possible both skipping the hydration phase and decreasing the risk of accidental exposure of material to pathogens during manipulation and grafting phases; furthermore the syringe is flexible and ideal to simplify grafting in the receiving site. 

The granules are endowed with characteristics very similar to human mineral bone, and can be used as an alternative to autologous bone. Their natural micro-porous consistency facilitates new bone tissue formation in defect sites and accelerates the regeneration process.

Gradually resorbable, it preserves the original graft shape and volume (osteoconductive property). Moreover, thanks to its collagen content, the product facilitates blood clotting and the subsequent invasion of repairing and regenerative cells.

Handling: mp3 is available in ready-to-use syringes and can be easily grafted avoiding the hydration and manipulation phases. After adapting the material to the defect shape, it is necessary to remove non stable residues before proceeding to soft tissue suture.


Oral surgery and implantology: thanks to its particular formulation and granulometry, mp3 is ideal for grafting in surgical procedures of maxillary sinus lift with lateral access. A membrane OsteoBiol Evolution or Special is recommended to cover the antrostomy.


A bone graft is a material used to repair a bone defect or deficiency contour and/or volume. The use of these materials in regenerative procedures is based on the assumption that they are osteoconductive i.e. serve as scaffold for new bone formation.

The entire OsteoBiol line consists of xenografts, i.e. biomaterials deriving from heterologous bone and soft tissues. The Tecnoss patented manufacturing process used to obtain these materials is able to achieve biocompatibility preserving part of the collagen matrix of the animal bone and avoiding at the same time high temperatures that would cause ceramization of the granules: the result is a unique biomaterial, consisting of mineral component and organic matrix, with a porous surface extremely similar to autogenous bone and able to resorb progressively while new bone formation takes place.

mp3, a pre-hydrated cortico-cancellous bone mix with 10% collagen gel, has been developed with this innovative biotechnology and is a "ready to use" product. 

mp3 main indication is lateral access maxillary sinus lift, always in association with Evolution membranes: the mp3 syringe can be directly applied into the bony window without having to mix the mp3 granules with saline. Due to its collagen gel content, mp3 allows an excellent graft stability while its hydrophilia guarantees quick blood absorption and therefore the necessary graft vascularization. 

mp3 has also been successfully used in combination with Evolution membranes for alveolar ridge preservation: the application of this biomaterial limits significantly the alveolar ridge width and height reduction that would naturally occur with spontaneous healing, preserving thus the alveolar ridge volume and allowing a correct second stage implant placement.

Finally, mp3 is indicated for horizontal augmentation (two wall defects) in combination with autogenous bone blocks or with OsteoBiol Cortical Lamina: its cortico-cancellous composition allows a progressive resorption of osteoclastic type, with in parallel a similar rate of new bone formation. These unique properties allow a very good graft volume preservation, a healthy new bony tissue and ultimately, a successful implant rehabilitation.